1. kolo
| 10.09.2021. | Paris Saint-Germain | 34:25 | Istres | - |
| 10.09.2021. | Créteil | 34:29 | Dunkerque | - |
| 10.09.2021. | Nîmes | 31:26 | Saran HB | - |
| 10.09.2021. | Toulouse | 27:30 | Chambéry | - |
| 10.09.2021. | Aix | 31:29 | Limoges | - |
| 10.09.2021. | Cesson Rennes | 29:27 | Nantes | - |
| 10.09.2021. | Chartres | 28:27 | Nancy | - |
| 10.09.2021. | Montpellier | 29:29 | Saint-Raphaël | - |
2. kolo
| 16.09.2021. 20:00 | Saran HB | 25:28 | Créteil | - |
4. kolo
| 02.10.2021. 19:00 | Paris Saint-Germain | -:- | Cesson Rennes | - |
| 02.10.2021. 20:00 | Aix | -:- | Nantes | - |
12. kolo
| 02.12.2021. 20:00 | Istres | -:- | Saint-Raphaël | - |
| 02.12.2021. 20:15 | Chambéry | 31:27 | Cesson Rennes | - |
| 03.12.2021. 19:00 | Chartres | 27:26 | Dunkerque | - |
| 03.12.2021. 20:30 | Créteil | 32:31 | Limoges | - |
| 04.12.2021. 20:30 | Nîmes | 26:34 | Nantes | - |
| 05.12.2021. 15:30 | Toulouse | 32:26 | Montpellier | - |
| 05.12.2021. 17:00 | Paris Saint-Germain | 38:26 | Nancy | - |
| 08.02.2022. 20:00 | Aix | 32:26 | Saran HB | - |
13. kolo
| 09.12.2021. 20:30 | Cesson Rennes | 30:30 | Istres | - |
| 10.12.2021. 20:30 | Nancy | 24:28 | Nîmes | - |
| 10.12.2021. 20:30 | Toulouse | 28:28 | Créteil | - |
| 11.12.2021. 20:00 | Montpellier | 32:21 | Chartres | - |
| 11.12.2021. 20:45 | Nantes | 38:29 | Chambéry | - |
| 12.12.2021. 18:30 | Saint-Raphaël | 24:31 | Aix | - |
14. kolo
| 14.12.2021. 20:00 | Istres | 26:26 | Créteil | - |
| 14.12.2021. 20:15 | Chambéry | 32:26 | Nancy | - |
| 14.12.2021. 20:30 | Nantes | 29:30 | Paris Saint-Germain | - |
| 15.12.2021. 20:00 | Aix | 29:31 | Toulouse | - |
| 15.12.2021. 20:00 | Dunkerque | 29:28 | Cesson Rennes | - |
| 15.12.2021. 20:00 | Saran HB | 26:32 | Chartres | - |
| 15.12.2021. 20:30 | Nîmes | 23:30 | Saint-Raphaël | - |
| 09.02.2022. 20:00 | Limoges | -:- | Montpellier | - |
15. kolo
| 04.02.2022. 20:00 | Cesson Rennes | 24:24 | Nîmes | - |
| 04.02.2022. 20:30 | Nancy | 27:29 | Limoges | - |
| 05.02.2022. 20:00 | Chartres | 31:32 | Aix | - |
| 05.02.2022. 20:00 | Montpellier | 26:22 | Saran HB | - |
| 05.02.2022. 20:00 | Paris Saint-Germain | 38:30 | Dunkerque | - |
| 05.02.2022. 20:00 | Toulouse | 30:25 | Istres | - |
| 05.02.2022. 20:30 | Créteil | 29:31 | Chambéry | - |
| 06.02.2022. 17:00 | Saint-Raphaël | 27:36 | Nantes | - |
16. kolo
| 11.02.2022. 20:00 | Aix | -:- | Nancy | - |
| 11.02.2022. 20:00 | Chambéry | -:- | Toulouse | - |
| 11.02.2022. 20:00 | Istres | -:- | Paris Saint-Germain | - |
| 11.02.2022. 20:00 | Nîmes | -:- | Créteil | - |
| 12.02.2022. 20:00 | Nantes | -:- | Saint-Raphaël | - |
| 12.02.2022. 20:30 | Saran HB | -:- | Cesson Rennes | - |
| 13.02.2022. 15:30 | Dunkerque | -:- | Montpellier | - |
| 13.02.2022. 17:00 | Limoges | -:- | Chartres | - |
