Liga prvaka, skupina A
1. kolo
| 26.10.2021. 18:15 | Olympiakos | 20:9 | Dinamo Tbilisi | - |
| 26.10.2021. 19:15 | Barceloneta | 11:6 | Jadran Split | Izvještaj |
| 26.10.2021. 19:45 | Novi Beograd | 16:10 | Radnički | - |
| 26.10.2021. 20:30 | Brescia | 8:8 | Ferencvaros | - |
2. kolo
| 09.11.2021. 19:00 | Jadran Split | 15:13 | Dinamo Tbilisi | Izvještaj |
| 09.11.2021. 19:00 | Novi Beograd | 9:12 | Olympiakos | - |
| 09.11.2021. 19:00 | Brescia | 14:12 | Barceloneta | - |
| 09.11.2021. 19:00 | Radnički | 11:11 | Ferencvaros | - |
3. kolo
| 19.11.2021. | Ferencvaros | 9:9 | Olympiakos | - |
| 19.11.2021. | Radnički | 8:14 | Brescia | - |
| 19.11.2021. | Dinamo Tbilisi | 7:20 | Barceloneta | - |
| 19.11.2021. | Jadran Split | 12:17 | Novi Beograd | - |
4. kolo
| 30.11.2021. 16:00 | Dinamo Tbilisi | 11:19 | Brescia | - |
| 30.11.2021. 18:15 | Olympiakos | 8:4 | Barceloneta | - |
| 30.11.2021. 19:00 | Jadran Split | 9:8 | Radnički | Izvještaj |
| 30.11.2021. 20:30 | Ferencvaros | 11:10 | Novi Beograd | - |
5. kolo
| 14.12.2021. 18:15 | Olympiakos | 12:10 | Jadran Split | Izvještaj |
| 14.12.2021. 19:00 | Barceloneta | 12:12 | Ferencvaros | - |
| 14.12.2021. 19:45 | Novi Beograd | 11:11 | Brescia | - |
| 14.12.2021. 20:30 | Radnički | 14:7 | Dinamo Tbilisi | - |
6. kolo
| 21.12.2021. 19:00 | Barceloneta | 13:7 | Radnički | - |
| 21.12.2021. 20:30 | Brescia | 8:7 | Olympiakos | - |
| 21.12.2021. 20:30 | Ferencvaros | 14:8 | Jadran Split | Izvještaj |
| 22.12.2021. 16:00 | Dinamo Tbilisi | 8:17 | Novi Beograd | - |
7. kolo
| 11.01.2022. 16:00 | Dinamo Tbilisi | 7:14 | Ferencvaros | - |
| 11.01.2022. 16:30 | Olympiakos | 11:7 | Radnički | - |
| 11.01.2022. 20:15 | Barceloneta | 12:12 | Novi Beograd | - |
| 11.01.2022. 20:30 | Brescia | 6:5 | Jadran Split | Izvještaj |
9. kolo
| 08.02.2022. 18:15 | Olympiakos | 5:8 | Brescia | - |
| 09.02.2022. 19:00 | Radnički | -:- | Barceloneta | - |
| 09.02.2022. 19:00 | Jadran Split | 9:7 | Ferencvaros | Izvještaj |
| 09.02.2022. 19:45 | Novi Beograd | -:- | Dinamo Tbilisi | - |
10. kolo
Liga prvaka, skupina B
1. kolo
| 27.10.2021. 18:00 | OSC Budimpešta | 14:8 | Steaua | - |
| 27.10.2021. 19:00 | Jug AO | 13:7 | Hannover | Izvještaj |
| 27.10.2021. 20:00 | Crvena zvezda | 12:9 | Spandau | - |
| 27.10.2021. 20:30 | Marseille | 7:13 | Pro Recco | - |
4. kolo
| 01.12.2021. 19:00 | OSC Budimpešta | 9:14 | Marseille | - |
| 01.12.2021. 19:00 | Steaua | 8:10 | Jug AO | Izvještaj |
| 01.12.2021. 20:15 | Crvena zvezda | 12:15 | Hannover | - |
| 01.12.2021. 20:30 | Pro Recco | 14:9 | Spandau | - |
5. kolo
| 15.12.2021. 19:00 | Marseille | 13:10 | Hannover | - |
| 15.12.2021. 19:00 | OSC Budimpešta | 8:14 | Pro Recco | - |
| 15.12.2021. 19:00 | Spandau | 10:8 | Steaua | - |
| 15.12.2021. 20:00 | Crvena zvezda | 13:19 | Jug AO | Izvještaj |
6. kolo
| 22.12.2021. 19:00 | Hannover | 7:20 | Pro Recco | - |
| 22.12.2021. 19:00 | Jug AO | 11:12 | OSC Budimpešta | Izvještaj |
| 22.12.2021. 19:00 | Marseille | 12:7 | Spandau | - |
| 22.12.2021. 19:00 | Steaua | 11:8 | Crvena zvezda | - |
7. kolo
9. kolo
| 08.02.2022. 19:00 | OSC Budimpešta | 10:15 | Jug AO | Izvještaj |
| 08.02.2022. 19:00 | Spandau | 7:13 | Marseille | - |
| 08.02.2022. 20:00 | Crvena zvezda | 10:10 | Steaua | - |
| 08.02.2022. 21:00 | Pro Recco | 18:3 | Hannover | - |
11. kolo
| 29.03.2022. 19:00 | Jug AO | 14:7 | Steaua | Izvještaj |
| 29.03.2022. 19:00 | Spandau | 6:11 | Pro Recco | - |
| 29.03.2022. 19:00 | Marseille | 13:9 | OSC Budimpešta | - |
| 29.03.2022. 19:00 | Hannover | 14:11 | Crvena zvezda | - |
13. kolo
